Creighton Tuzon

CSA 210, HSC 9062
Phone: (323) 442-1318
Fax: (323) 442-2981

Creighton Tuzon, Ph.D.

Research Associate, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA

  • University of Hawaii, Honolulu

  • University of Colorado HSC, Denver
    Biochemistry & Molecular Genetics

  • 2015 - present - Research Associate - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2010 - 2015 - Postdoctoral Research Fellow - Department of Biochemistry and Molecular Biology, University of Southern California.
  • 2005 - 2010 - Postdoctoral Research Fellow - Department of Molecular Biology, Princeton University
  • 1997 - 1998 - Research Technician - Department of Medicine, University of Hawaii at Manoa.
  • 1995 - 1997 - Research Technician - Genetics Laboratory-USDA Human Nutrition Research Center, Tufts University.
  1. Neben CL, Lay FD, Mao X, Tuzon CT, Merrill AE. (2017) Ribosome biogenesis is dynamically regulated during osteoblast differentiation. Gene. 2017 May 15;612:29-35. doi: 10.1016/j.gene.2016.11.010. Epub 2016 Nov 12. PubMed PMID: 27847259; PubMed Central PMCID: PMC5382099.

  2. Neben CL, Tuzon CT, Mao X, Lay FD, Merrill AE. (2017) FGFR2 Mutations in Bent Bone Dysplasia Syndrome Activate Nucleolar Stress and Perturb Cell Fate Determination. Hum Mol Genet. 2017 Jun 8. doi: 10.1093/hmg/ddx209. [Epub ahead of print] PubMed PMID: 28595297.

  3. Dieli-Conwright CM, Kiwata JL, Tuzon C, Spektor TM, Sattler FR, Rice JC, Schroeder ET. (2015) Acute response of PGC-1a and IGF-1 isoforms to maximal eccentric exercise in skeletal muscle of postmenopausal women. J Strength Cond Res. 2016 Apr;30(4):1161-70. doi: 10.1519/JSC.0000000000001171. PubMed PMID: 26340467; PubMed Central PMCID: PMC4769997.

  4. Neben CL, Idoni B, Salva JE, Tuzon CT, Rice JC, Krakow D, Merrill AE. (2014) Bent bone dysplasia syndrome reveals nucleolar activity for FGFR2 in ribosomal DNA transcription. Hum Mol Genet. 2014 Nov 1;23(21):5659-71. doi: 10.1093/hmg/ddu282. Epub 2014 Jun 6. PubMed PMID: 24908667; PubMed Central PMCID: PMC4189901.

  5. Tuzon CT, Spektor T, Kong X, Congdon LM, Wu S, Schotta G, Yokomori K, Rice JC. (2014) Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair. Cell Rep. 2014 Jul 24;8(2):430-8. doi: 10.1016/j.celrep.2014.06.013. Epub 2014 Jul 4. PubMed PMID:25001286; PubMed Central PMCID: PMC4134327.

  6. Congdon LM, Sims JK, Tuzon CT, Rice JC. (2014) The PR-Set7 binding domain of Riz1 is required for the H4K20me1-H3K9me1 trans-tail histone code and Riz1 tumor suppressor function. Nucleic Acids Res. 2014 Apr;42(6):3580-9. doi:10.1093/nar/gkt1377. Epub 2014 Jan 13. PubMed PMID: 24423864; PubMed Central PMCID: PMC3973283.

  7. Tuzon CT, Wu Y, Chan A, Zakian VA. (2011) The Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitro. PLoS Genet. 2011 May;7(5):e1002060. doi: 10.1371/journal.pgen.1002060. Epub 2011 May 5. PubMed PMID: 21573139; PubMed Central PMCID: PMC3088721.

  8. Sabourin M, Tuzon CT, Zakian VA. (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol Cell. 2007 Aug 17;27(4):550-61. Epub 2007 Jul 26. PubMed PMID: 17656141; PubMed Central PMCID: PMC2650483.

  9. Sabourin M, Tuzon CT, Fisher TS, Zakian VA. (2007) A flexible protein linker improves the function of epitope-tagged proteins in Saccharomyces cerevisiae. Yeast. 2007 Jan;24(1):39-45. PubMed PMID: 17192851; PubMed Central PMCID: PMC3518027.

  10. Goudsouzian LK, Tuzon CT, Zakian VA. (2006) S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol Cell. 2006 Nov 17;24(4):603-10. PubMed PMID: 17188035.

  11. Tuzon CT, Borgstrom B, Weilguny D, Egel R, Cooper JP, Nielsen O. (2004) The fission yeast heterochromatin protein Rik1 is required for telomere clustering during meiosis. J Cell Biol. 2004 Jun 21;165(6):759-65. Epub 2004 Jun 14. PubMed PMID: 15197176; PubMed Central PMCID: PMC2172399.

  12. Palmer HJ, Tuzon CT, Paulson KE. (1999) Age-dependent decline in EGF-induced signaling is independent of intracellular thiols. Age (Omaha). 1999 Oct;22(4):167-73. doi: 10.1007/s11357-999-0019-y. PubMed PMID: 23604425; PubMed Central PMCID: PMC3455412.

  13. Palmer HJ, Tuzon CT, Paulson KE. (1999) Age-dependent decline in mitogenic stimulation of hepatocytes. Reduced association between Shc and the epidermal growth factor receptor is coupled to decreased activation of Raf and extracellular signal-regulated kinases. J Biol Chem. 1999 Apr 16;274(16):11424-30. PubMed PMID: 10196236.