Satyajit Mitra

CSA 210, HSC 9062
Phone: (323) 442-2549
Fax: (323) 442-2981
satyajim@usc.edu

Satyajit Mitra, Ph.D.

Research Scientist, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA

  • Ramnarain Ruia College (affiliated with) University of Mumbai, Mumbai, India
    B.S.
    1994
    Microbiology

  • University of Baroda, Gujarat, India
    M.S.
    1996
    Biotechnology

  • Hyderabad Jawaharlal Nehru University, New Delhi, India
    Ph.D.
    2001
    Cell Biology

  • 2016 - present - Research Scientist - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2011 - 2012 - Senior Scientist - VasGene Therapeutics, Los Angeles, CA
  • 2006 - 2011 - Scientist - OncoMed Pharmaceuticals, Redwood City, CA
  • 2002 - 2006 - Post-doctoral Research Associate - David Schlaepfer lab, Dept. of Immunology, The Scripps Research Institute, La Jolla, CA
  • 1997 - 2001 - Graduate Student - Centre for Cellular and Molecular Biology, Hyderabad, India
  1. Liu R, Li X, Gao W, Zhou Y, Wey S, Mitra SK, Krasnoperov V, Dong D, Liu S, Li D, Zhu G, Louie S, Conti PS, Li Z, Lee AS, Gill PS. (2013) Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis. Clin Cancer Res. 2013 Dec 15;19(24):6802-11. doi:10.1158/1078-0432.CCR-13-1106. Epub 2013 Sep 18. PubMed PMID: 24048331; PubMed Central PMCID: PMC4151476.

  2. Gurney A, Axelrod F, Bond CJ, Cain J, Chartier C, Donigan L, Fischer M, Chaudhari A, Ji M, Kapoun AM, Lam A, Lazetic S, Ma S, Mitra S, Park IK, Pickell K, Sato A, Satyal S, Stroud M, Tran H, Yen WC, Lewicki J, Hoey T. (2012) Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11717-22. doi: 10.1073/pnas.1120068109. Epub 2012 Jul 2. PubMed PMID: 22753465; PubMed Central PMCID: PMC3406803.

  3. Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD. (2008) Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility. Oncogene. 2008 Feb 28;27(10):1439-48. Epub 2007 Sep 10. PubMed PMID: 17828307; PubMed Central PMCID: PMC2593630.

  4. Schlaepfer DD, Hou S, Lim ST, Tomar A, Yu H, Lim Y, Hanson DA, Uryu SA, Molina J, Mitra SK. (2007) Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. J Biol Chem. 2007 Jun 15;282(24):17450-9. Epub 2007 Apr 16. PubMed PMID: 17438336.

  5. Mitra SK, Schlaepfer DD. (2006) Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol. 2006 Oct;18(5):516-23. Epub 2006 Aug 17. Review. PubMed PMID: 16919435.

  6. Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. (2006) Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 2006 Sep 28;25(44):5969-84. Epub 2006 May 8. PubMed PMID: 16682956.

  7. Mitra SK, Lim ST, Chi A, Schlaepfer DD. (2006) Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model. Oncogene. 2006 Jul 27;25(32):4429-40. Epub 2006 Mar 20. PubMed PMID: 16547501.

  8. Hsia DA, Lim ST, Bernard-Trifilo JA, Mitra SK, Tanaka S, den Hertog J, Streblow DN, Ilic D, Ginsberg MH, Schlaepfer DD. (2005) Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Mol Cell Biol. 2005 Nov;25(21):9700-12. PubMed PMID: 16227616; PubMed Central PMCID: PMC1265817.

  9. Mitra SK, Hanson DA, Schlaepfer DD. (2005) Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol. 2005 Jan;6(1):56-68. Review. PubMed PMID: 15688067.

  10. Schlaepfer DD, Mitra SK, Ilic D. (2004) Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochim Biophys Acta. 2004 Jul 5;1692(2-3):77-102. Review. PubMed PMID: 15246681.

  11. Schlaepfer DD, Mitra SK. (2004) Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev. 2004 Feb;14(1):92-101. Review. PubMed PMID: 15108811.

  12. Hsia DA, Mitra SK, Hauck CR, Streblow DN, Nelson JA, Ilic D, Huang S, Li E, Nemerow GR, Leng J, Spencer KS, Cheresh DA, Schlaepfer DD. (2003) Differential regulation of cell motility and invasion by FAK. J Cell Biol. 2003 Mar 3;160(5):753-67. PubMed PMID: 12615911; PubMed Central PMCID: PMC2173366.

  13. Mitra SK, Swarup G. (2001) Inhibition of anchorage-independent cell growth, adhesion, and cyclin D1 gene expression by a dominant negative mutant of a tyrosine phosphatase. Exp Cell Res. 2001 Oct 15;270(1):32-44. PubMed PMID: 11597125.