Ya-Ping Lei

CSA 133, HSC 9062
Phone: (323)442-3165
Fax: (323)442-2981
lei@usc.edu

Ya-Ping Lei, M.S.

Research Lab Specialist, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA

  • Shanxi Medical University, P.R. China
    B.A.
    1983
    Medicine

  • Graduate school, Chinese Academic of Science, Peking Union Medical College, China
    M.S.
    1987
    Cardiology

  • University of Southern California, CA
    M.S.
    2000
    Biochemistry and Molecular Biology

  • 2007 - present - Research Lab Specialist - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 1993 - 2007 - Research Lab Technician III/Supervisor - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 1992 - 1993 - Research Associate - Children' s Hospital of Los Angeles, Los Angeles, CA
  • 1990 - 1992 - Research Associate - Medical School, University of Southern California, Los Angeles, CA
  • 1987 - 1990 - Physician in charge - Cardiology Institute and Fuwai Hospital, P. R. China
  1. Huang Z, Newcomb CJ, Lei Y, Zhou Y, Bornstein P, Amendt BA, Stupp SI, Snead ML. (2015) Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration. Biomaterials. 2015 Aug;61:216-28. doi:10.1016/j.biomaterials.2015.05.035. PubMed PMID: 26004236; PubMed Central PMCID: PMC4467543.

  2. Yin K, Lei Y, Wen X, Lacruz RS, Soleimani M, Kurtz I, Snead ML, White SN, Paine ML. (2015) SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. PLoS One. 2015 Dec 15;10(12):e0144703. doi:10.1371/journal.pone.0144703. eCollection 2015. PubMed PMID: 26671068; PubMed Central PMCID: PMC4679777.

  3. Huang Z, Newcomb CJ, Zhou Y, Lei YP, Bringas P Jr, Stupp SI, Snead ML. (2013) The role of bioactive nanofibers in enamel regeneration mediated through integrin signals acting upon C/EBPα and c-Jun. Biomaterials. 2013 Apr;34(13):3303-14. doi: 10.1016/j.biomaterials.2013.01.054. Epub 2013 Feb 9. PubMed PMID: 23398885; PubMed Central PMCID: PMC3600413.

  4. Snead ML, Zhu DH, Lei Y, Luo W, Bringas PO Jr, Sucov HM, Rauth RJ, Paine ML, White SN. (2011) A simplified genetic design for mammalian enamel. Biomaterials. 2011 Apr;32(12):3151-7. Epub 2011 Feb 5. PubMed PMID: 21295848; PubMed Central PMCID: PMC3045652.

  5. Bromley KM, Lakshminarayanan R, Lei YP, Snead ML, Moradian-Oldak J. (2011) Folding, Assembly, and Aggregation of Recombinant Murine Amelogenins with T21I and P41T Point Mutations. Cells Tissues Organs. 2011;194(2-4):284-90. Epub 2011 May 2.PubMed PMID: 21540557; PubMed Central PMCID: PMC3178092.

  6. Laksminarayanan R, Bromley KM, Lei YP, Snead ML, Moradian-Oldak J. (2010) Perturbed amelogenin secondary structure leads to uncontrolled aggregation in amelogenesis imperfecta mutant proteins. J Biol Chem. 2010 Dec 24;285(52):40593-603. Epub 2010 Oct 7. PubMed PMID: 20929860; PubMed Central PMCID: PMC3003358.

  7. Wen X, Lei YP, Zhou YL, Okamoto CT, Snead ML, Paine ML. (2005) Structural organization and cellular localization of tuftelin-interacting protein 11 (TFIP11). Cell Mol Life Sci. 62(9):1038-46.

  8. Paine ML, Lei YP, Dickerson K, Snead ML. (2002) Altered Amelogenin Self-assembly Based on Mutations Observed in Human X-linked Amelogenesis Imperfecta (AIH1). J Biol Chem 10;277(19):17112-6

  9. Zhou YL, Lei Y, Snead ML (2000) Functional antagonism between Msx2 and CCAAT/enhancer-binding protein alpha in regulating the mouse amelogenin gene expression is mediated by protein-protein interaction. J Biol Chem 275:29066-75

  10. Paine ML, Zhu DH, Luo W, Bringas P Jr, Goldberg M, White SN, Lei YP, Sarikaya M, Fong HK, Snead ML (2000) Enamel biomineralization defects result from alterations to amelogenin self-assembly. J Struct Biol 132(3):191-200

  11. Moradian-Oldak J, Paine ML, Lei YP, Fincham AG, Snead ML (2000) Self-assembly properties of recombinant engineered amelogenin proteins analyzed by dynamic light scattering and atomic force microscopy. J Struct Biol 131(1):27-37

  12. Snead ML, Paine ML, Luo W, Zhu DH, Yoshida B, Lei YP, Chen LS, Paine CT, Burstein JM, Jitpukdeebudintra S, White SN, Bringas P Jr (1998) Transgene Animal Model for Protein Expression and Accumulation into forming Enamel. Connective Tissue Research 38(1-4), pp. 279-286.

  13. Snead ML, Paine ML, Chen LS, Yoshida B, Luo W, Zhou D, Lei YP, Liu YH, Maxson RE (1996) The murine amelogenin promoter: Developmentally regulated expression in transgenic animals. Conn. Tiss. Res. 35:1-4, pp. 41-47.

  14. Snead ML, Paine ML, Chen LS, Yoshida B, Luo W, Zhu DH, Lei YP, Liu YH, Maxson RE (1996) The murine amelogenin promoter: Developmentally regulated expression in transgenic animals. Conn. Tiss. Res. 35:1-4, pp. 41-47.