Carolina Parada Borja

CSA 146 HSC 9062
Phone: (323)442-3191
Fax: (323)442-2981

Carolina Parada Borja, D.M.D., Ph.D.

Research Associate, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA

  • National University of Colombia, Colombia

  • University of Barcelona, Spain

  • 2014 - present - Research Associate - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2009 - 2014 - Postdoctoral Research Associate - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2008 - 2009 - Postdoctoral Fellow - University Pompeu Fabra Barcelona Biomedical Research Park, Spain
  • 2004 - 2008 - Ph.D. Student - Genetics Department, University of Barcelona, Spain
  • 2003 - Researcher - Institute of Biotechnology, National University of Colombia
  • 2001 - 2003 - Researcher - Institute of Genetics, National University of Colombia
  1. Li J, Parada C, Chai Y. (2017) Cellular and molecular mechanisms of tooth root development. Development. 2017 Feb 1;144(3):374-384. doi: 10.1242/dev.137216. Review. PubMed PMID: 28143844; PubMed Central PMCID: PMC5341797.

  2. Sugii H, Grimaldi A, Li J, Parada C, Vu-Ho T, Feng J, Jing J, Yuan Y, Guo Y, Maeda H, Chai Y. (2017) Dlx5-FGF10 signaling cascade controls cranial neural crest and myoblast interaction during oropharyngeal patterning and development. Development. 2017 Nov 1;144(21):4037-4045. doi: 10.1242/dev.155176. Epub 2017 Oct 5. PubMed PMID: 28982687; PubMed Central PMCID: PMC5702075.

  3. Parada C, Han D, Grimaldi A, Sarrión P, Park SS, Pelikan R, Sanchez-Lara PA, Chai Y. (2015) Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development. 2015 Nov 1;142(21):3734-45. doi:10.1242/dev.125328. Epub 2015 Sep 22. PubMed PMID: 26395480; PubMed Central PMCID: PMC4647211.

  4. Parada C, Chai Y. (2015) Mandible and Tongue Development. Curr Top Dev Biol.2015;115:31-58. doi: 10.1016/bs.ctdb.2015.07.023. Epub 2015 Oct 1. PubMed PMID:26589920; PubMed Central PMCID: PMC4869709.

  5. Grimaldi A, Parada C, Chai Y. (2015) A Comprehensive Study of Soft Palate Development in Mice. PLoS One. 2015 Dec 15;10(12):e0145018. doi:10.1371/journal.pone.0145018. eCollection 2015. PubMed PMID: 26671681; PubMed Central PMCID: PMC4687642.

  6. Parada C, Li J, Iwata J, Suzuki A, Chai Y. (2013) CTGF Mediates Smad-Dependent Transforming Growth Factor β Signaling To Regulate Mesenchymal Cell Proliferation during Palate Development. Mol Cell Biol. 2013 Sep;33(17):3482-93. doi:10.1128/MCB.00615-13. Epub 2013 Jul 1. PubMed PMID: 23816882; PubMed Central PMCID: PMC3753855.

  7. Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y. (2012) Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor beta (TGFb) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J Biol Chem. 2012 Jan 20;287(4):2353-63. Epub 2011 Nov 28. PubMed PMID: 22123828;PubMed Central PMCID: PMC3268397.

  8. Parada C, Han D, Chai Y. (2012) Molecular and Cellular Regulatory Mechanisms of Tongue Myogenesis. J Dent Res. 2012 Jun;91(6):528-35. Epub 2012 Jan 4. Review.PubMed PMID: 22219210; PubMed Central PMCID: PMC3348065.

  9. Han D, Zhao H, Parada C, Hacia JG, Bringas, Jr. P, Chai Y. (2012) A TGF-beta-Smad4-FGF6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development Development. 2012 May;139(9):1640-50. Epub 2012 Mar 21.PubMed PMID: 22438570; PubMed Central PMCID: PMC3317969.

  10. Parada C, Chai Y. (2012) Roles of BMP signaling pathway in lip and palate development. Front Oral Biol. 2012;16:60-70. doi: 10.1159/000337617. Epub 2012 Jun 25. Review. PubMed PMID: 22759670; PubMed Central PMCID: PMC3661199.

  11. Neves J*, Parada C*, Chamizo M, Giráldez F. (2011) Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification. Development. 2011 Feb;138(4):735-44. PubMed PMID: 21266409. (*Equally contributing authors).

  12. Iwata J, Parada C, Chai Y. (2011) The mechanism of TGF-beta signaling during palatogenesis. Oral Dis. 2011 Nov;17(8):733-44. doi:10.1111/j.1601-0825.2011.01806.x. Epub 2011 Mar 13. Review. PubMed PMID:21395922; PubMed Central PMCID: PMC3329177.

  13. Lang M, Hadzhiev Y, Siegel N, Amemiya CT, Parada C, Strähle U, Becker MB, Müller F, Meyer A. (2010) Conservation of shh cis-regulatory architecture of the coelacanth is consistent with its ancestral phylogenetic position. Evodevo. 2010 Nov 3;1(1):11. PubMed PMID: 21047394; PubMed Central PMCID: PMC2992049.

  14. Parvas M, Parada C, Bueno D. (2008) A Blood-CSF Barrier Function Controls the Embryonic CSF Protein Composition and Homeostasis during Early CNS Development. Developmental Biology. 321(1):51-63. PubMed PMID: 18632096.

  15. Parada C, Escola-Gil JC, Bueno D (2008) Low-density lipoproteins from Embryonic Cerebrospinal Fluid are required for neural differentiation Journal of Neuroscience Research, 86: 2674-2684. PubMed PMID: 18500757.

  16. Parada C, Gato A, Bueno D. (2008) All-trans retinol and RBP from E-CSF exhibit dynamic behaviour during early CNS development. Neuroreport. 2008 Jun 11;19(9):945-50. PubMed PMID: 18520998.

  17. Parada C, Parvas M, Bueno D. (2007) Cerebrospinal fluid proteomes: from neural development to neurodegenerative diseases. Current Proteomics, 4, 89-106.

  18. Parada C, Gato A, Aparicio M, Bueno D. (2006) Proteome analysis of chick embryonic cerebrospinal fluid. Proteomics 2006, 6(1):312320.

  19. Martin C, Bueno D, Alonso MI, Moro JA, Callejo S, Parada C, Martin P, Gato A. (2006) FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells. Developmental Biology, 297(2):402-416. PubMed PMID: 16916506.

  20. Parada C, Gato A, Bueno D. (2005) Mammalian Embryonic Cerebrospinal Fluid Proteome Has Greater Apolipoprotein and Enzyme Pattern Complexity than the Avian Proteome. Journal of Proteome Research, 4(6):2420-2428.

  21. Parada C, Martin C, Alonso MI, Moro J, Bueno D, Gato A. (2005) Embryonic Cerebrospinal Fluid Collaborates With the Isthmic Organizer To Regulate Mesencephalic Gene Expression. Journal of Neuroscience Research, 82(3):333-345.