Richard Pelikan

CSA 210, HSC 9062
Phone: (323) 442-2549
Fax: (323) 442-2981

Richard Pelikan, Ph.D.

Postdoctoral Research Associate, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA

  • University of Pittsburgh
    Computer Science

  • University of Pittsburgh
    Computer Science

  • University of Pittsburgh
    Intelligent Systems/ Biomedical Informatics

  • 2011 - Present - Postdoctoral Research Associate - Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2005 - 2011 - Research Assistant - Intelligent Systems Program, University of Pittsburgh
  • 2005 - 2011 - NLM Training Fellow - Department of Biomedical Informatics, University of Pittsburgh
  • 2002 - 2005 - Research Assistant - Department of Computer Science, University of Pittsburgh
  1. Parada C, Han D, Grimaldi A, Sarrión P, Park SS, Pelikan R, Sanchez-Lara PA, Chai Y. (2015) Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development. 2015 Nov 1;142(21):3734-45. doi:10.1242/dev.125328. Epub 2015 Sep 22. PubMed PMID: 26395480; PubMed Central PMCID: PMC4647211.

  2. Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Chai Y. (2014) Modulation of Lipid Metabolic Defects Rescues Cleft Palate in Tgfbr2 Mutant Mice. Hum Mol Genet. 2014 Jan 1;23(1):182-93. doi: 10.1093/hmg/ddt410. Epub 2013 Aug 23. PubMed PMID: 23975680; PubMed Central PMCID: PMC3857953.

  3. Iwata J, Suzuki A, Yokota T, Ho TV, Pelikan R, Urata M, Sanchez-Lara PA, Chai Y. (2014) TGFβ regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate. Development. 2014 Feb;141(4):909-17. doi: 10.1242/dev.103093. PubMed PMID: 24496627; PubMed Central PMCID: PMC3912833.

  4. Han A, Zhao H, Li J, Pelikan R, Chai Y. (2014) ALK5-Mediated Transforming Growth Factor β Signaling in Neural Crest Cells Controls Craniofacial Muscle Development via Tissue-Tissue Interactions. Mol Cell Biol. 2014 Aug 15;34(16):3120-31. doi:10.1128/MCB.00623-14. Epub 2014 Jun 9. PubMed PMID: 24912677; PubMed Central PMCID: PMC4135603.

  5. Pelikan RC, Iwata J, Suzuki A, Chai Y, Hacia JG. (2013) Identification of candidate downstream targets of TGF-bate signaling during palate development by genome-wide transcript profiling. J Cell Biochem. 2013 Apr;114(4):796-807. doi:10.1002/jcb.24417. PubMed PMID: 23060211; PubMed Central PMCID: PMC3777336.

  6. Iwata J, Suzuki A, Pelikan RC, Ho TV, Sanchez-Lara PA, Urata M, Dixon MJ, Chai Y. (2013) Smad4-Irf6 genetic interaction and TGF-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development. 2013 Mar;140(6):1220-30. doi: 10.1242/dev.089615. Epub 2013 Feb 13. PubMed PMID: 23406900; PubMed Central PMCID: PMC3585659.

  7. Iwata J, Suzuki A, Pelikan RC, Ho TV, Chai Y. (2013) Non-canonical transforming growth factor beta (TGFβ) signaling in cranial neural crest cells causes tongue muscle developmental defects. J Biol Chem. 2013 Oct 11;288(41):29760-70. doi:10.1074/jbc.M113.493551. Epub 2013 Aug 15. PubMed PMID: 23950180; PubMed Central PMCID: PMC3795273.

  8. Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y. (2012) Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor beta (TGFb) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J Biol Chem. 2012 Jan 20;287(4):2353-63. Epub 2011 Nov 28. PubMed PMID: 22123828;PubMed Central PMCID: PMC3268397.

  9. Pelikan R, Hauskrecht M. (2010) Efficient peak-labeling algorithms for whole-sample mass spectrometry proteomics. IEEE/ACM Trans Comput Biol Bioinform. 2010 Jan-Mar;7(1):126-37. PubMed PMID: 20150675.

  10. Pelikan RC, Hauskrecht M. (2010) Automatic selection of preprocessing methods for improving predictions on mass spectrometry protein profiles. AMIA Annu Symp Proc. 2010 Nov 13;2010:632-6. PubMed PMID: 21347055; PubMed Central PMCID: PMC3041275.

  11. Hauskrecht M, Pelikan R. (2008) Inter-session reproducibility measures for high-throughput data sources. Summit on Translat Bioinforma. 2008 Mar 1;2008:41-5. PubMed PMID: 21347125; PubMed Central PMCID: PMC3041518.

  12. Pelikan R, Bigbee WL, Malehorn D, Lyons-Weiler J, Hauskrecht M. (2007) Intersession reproducibility of mass spectrometry profiles and its effect on accuracy of multivariate classification models. Bioinformatics. 2007 Nov 15;23(22):3065-72. Epub 2007 Aug 30. PubMed PMID: 17766268.

  13. Pelikan R, Hauskrecht M. (2007) Peptide identification in whole-sample mass spectrometry proteomics. AMIA Annu Symp Proc. 2007 Oct 11:1073. PubMed PMID: 18694171.

  14. Jahnukainen T, Malehorn D, Sun M, Lyons-Weiler J, Bigbee W, Gupta G, Shapiro R, Randhawa PS, Pelikan R, Hauskrecht M, Vats A. (2006) Proteomic analysis of urine in kidney transplant patients with BK virus nephropathy. J Am Soc Nephrol. 2006 Nov;17(11):3248-56. Epub 2006 Oct 11. PubMed PMID: 17035609.

  15. Lyons-Weiler J, Pelikan R, Zeh HJ, Whitcomb DC, Malehorn DE, Bigbee WL, Hauskrecht M. (2005) Assessing the statistical significance of the achieved classification error of classifiers constructed using serum peptide profiles, and a prescription for random sampling repeated studies for massive high-throughput genomic and proteomic studies. Cancer Inform. 2005;1:53-77. PubMed PMID: 19305632; PubMed Central PMCID: PMC2657655.

  16. Hauskrecht M, Pelikan R, Malehorn DE, Bigbee WL, Lotze MT, Zeh HJ, Whitcomb DC, Lyons-Weiler J. (2005) Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles. Appl Bioinformatics. 2005;4(4):227-46. PubMed PMID: 16309341.